2,3-Diphosphoglyceric Acid

《英文msh詞典》2,3-Diphosphoglyceric Acid
[同義詞] 2,3-Diphosphoglyceric Acid
[主題詞] 2,3-Diphosphoglycerate
[中文釋義] 2,3-二磷酸甘油酸
[英文釋義] A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form,therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry,4th ed,p160; Enzyme Nomenclature,1992,p508)